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Nitrogen-doped graphene quantum dots coupled with photosensitizers for one-/two-photon activated photodynamic therapy based on a FRET mechanism

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Abstract

A novel material with a large two-photon absorption cross-section was conjugated with a typical photosensitizer for inducing a FRET process. The photosensitizer can be excited by a one-/two-photon laser and then induced photo-toxicity in vitro and in vivo. The system presents great potential for improving treatment depth and the precision of traditional photodynamic therapy.

Graphical abstract: Nitrogen-doped graphene quantum dots coupled with photosensitizers for one-/two-photon activated photodynamic therapy based on a FRET mechanism

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Publication details

The article was received on 16 Nov 2017, accepted on 29 Nov 2017 and first published on 29 Nov 2017


Article type: Communication
DOI: 10.1039/C7CC08820E
Citation: Chem. Commun., 2018, Advance Article
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    Nitrogen-doped graphene quantum dots coupled with photosensitizers for one-/two-photon activated photodynamic therapy based on a FRET mechanism

    J. Sun, Q. Xin, Y. Yang, H. Shah, H. Cao, Y. Qi, J. R. Gong and J. Li, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC08820E

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