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Large Stokes-shifted NIR-emission from Nanospace-induced Aggregation of Perylenemonoimide Doped Polymer Nanoparticle: Imaging of Folate Receptor Expression

Abstract

Development of a water-soluble, Perylene monoimide (PMI) dye-doped polymer nanoparticle (PNP) with NIR emission for live-cell imaging is demonstrated. The large Stokes-shifted NIR emission is due to confined nanospace-induced aggregation offered by the polymer matrix. Later, folic acid functionalised PNP (PNP-FA) is successfully employed to differentiate folate receptor positive and negative cancer cell.

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Publication details

The article was received on 01 Nov 2017, accepted on 05 Dec 2017 and first published on 06 Dec 2017


Article type: Communication
DOI: 10.1039/C7CC08404H
Citation: Chem. Commun., 2017, Accepted Manuscript
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    Large Stokes-shifted NIR-emission from Nanospace-induced Aggregation of Perylenemonoimide Doped Polymer Nanoparticle: Imaging of Folate Receptor Expression

    A. L. Koner, K. Pal, V. Sharma, D. Sahoo and N. Kapuria, Chem. Commun., 2017, Accepted Manuscript , DOI: 10.1039/C7CC08404H

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