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Issue 5, 2018
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Large Stokes-shifted NIR-emission from nanospace-induced aggregation of perylenemonoimide-doped polymer nanoparticles: imaging of folate receptor expression

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Abstract

The development of a water-soluble, perylenemonoimide (PMI) dye-doped polymer nanoparticle (PNP) with NIR emission for live-cell imaging is demonstrated. The large Stokes-shifted NIR emission is due to confined nanospace-induced aggregation offered by the polymer matrix. Later, folic acid functionalised PNP (PNP–FA) is successfully employed to differentiate folate receptor positive and negative cancer cells.

Graphical abstract: Large Stokes-shifted NIR-emission from nanospace-induced aggregation of perylenemonoimide-doped polymer nanoparticles: imaging of folate receptor expression

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Publication details

The article was received on 01 Nov 2017, accepted on 05 Dec 2017 and first published on 06 Dec 2017


Article type: Communication
DOI: 10.1039/C7CC08404H
Citation: Chem. Commun., 2018,54, 523-526
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    Large Stokes-shifted NIR-emission from nanospace-induced aggregation of perylenemonoimide-doped polymer nanoparticles: imaging of folate receptor expression

    K. Pal, V. Sharma, D. Sahoo, N. Kapuria and A. L. Koner, Chem. Commun., 2018, 54, 523
    DOI: 10.1039/C7CC08404H

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