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BEAMing LAMP: single-molecule capture and on-bead isothermal amplification for digital detection of hepatitis C virus in plasma

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Abstract

A novel dNAD platform (BEAMing LAMP) by combining emulsion micro-reactors, single-molecule magnetic capture and on-bead loop-mediated isothermal amplification has been developed for DNA detection, which enables absolute and high-precision quantification of a target with a detection limit of 300 copies.

Graphical abstract: BEAMing LAMP: single-molecule capture and on-bead isothermal amplification for digital detection of hepatitis C virus in plasma

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Publication details

The article was received on 01 Nov 2017, accepted on 05 Dec 2017 and first published on 06 Dec 2017


Article type: Communication
DOI: 10.1039/C7CC08403J
Citation: Chem. Commun., 2018, Advance Article
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    BEAMing LAMP: single-molecule capture and on-bead isothermal amplification for digital detection of hepatitis C virus in plasma

    J. Chen, X. Xu, Z. Huang, Y. Luo, L. Tang and J. Jiang, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC08403J

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