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Issue 100, 2017
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A chemoselective cleavable fluorescence turn-ON linker for proteomic studies

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Abstract

We have developed a trifunctional cleavable fluorescence turn-ON linker for chemoproteomic applications. This novel linker, which became highly fluorescent only upon cleavage of the azo bond, was successfully used for in situ proteome profiling/target identification and studies on newly synthesised proteomes.

Graphical abstract: A chemoselective cleavable fluorescence turn-ON linker for proteomic studies

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Publication details

The article was received on 25 Oct 2017, accepted on 24 Nov 2017 and first published on 24 Nov 2017


Article type: Communication
DOI: 10.1039/C7CC08235E
Citation: Chem. Commun., 2017,53, 13332-13335
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    A chemoselective cleavable fluorescence turn-ON linker for proteomic studies

    S. S. Liew, S. Du, J. Ge, S. Pan, S. Jang, J. Lee and S. Q. Yao, Chem. Commun., 2017, 53, 13332
    DOI: 10.1039/C7CC08235E

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