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Two-color vibrational imaging of glucose metabolism using stimulated Raman scattering

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Abstract

A two-color vibrational imaging technique for simultaneously mapping glucose uptake and incorporation activity inside single living cells is reported. Heterogeneous patterns of glucose metabolism are directly visualized from the ratiometric two-color images for various cell types, cells undergoing epithelia-to-mesenchymal transitions and live mouse brain tissues. The two-color imaging of glucose metabolism here demonstrates the development of multi-functional vibrational probes for multicolor imaging of cellular metabolism.

Graphical abstract: Two-color vibrational imaging of glucose metabolism using stimulated Raman scattering

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Publication details

The article was received on 24 Oct 2017, accepted on 23 Nov 2017 and first published on 23 Nov 2017


Article type: Communication
DOI: 10.1039/C7CC08217G
Citation: Chem. Commun., 2018, Advance Article
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    Two-color vibrational imaging of glucose metabolism using stimulated Raman scattering

    R. Long, L. Zhang, L. Shi, Y. Shen, F. Hu, C. Zeng and W. Min, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC08217G

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