Jump to main content
Jump to site search


Responsive DNA G-quadruplex micelles

Author affiliations

Abstract

A novel and versatile design of DNA–lipid conjugates is presented. The assembly of the DNA headgroups into G-quadruplex structures is essential for the formation of micelles and their stability. By hybridization with a complementary oligonucleotide the micelles were destabilized, resulting in cargo release. In combination with a hairpin DNA aptamer as complementary strand, the release is obtained selectively by the presence of ATP.

Graphical abstract: Responsive DNA G-quadruplex micelles

Back to tab navigation

Supplementary files

Publication details

The article was received on 16 Oct 2017, accepted on 06 Dec 2017 and first published on 06 Dec 2017


Article type: Communication
DOI: 10.1039/C7CC07899D
Citation: Chem. Commun., 2018, Advance Article
  •   Request permissions

    Responsive DNA G-quadruplex micelles

    L. Cozzoli, L. Gjonaj, M. C. A. Stuart, B. Poolman and G. Roelfes, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC07899D

Search articles by author

Spotlight

Advertisements