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A self-assessed photosensitizer: inducing and dual-modal phosphorescence imaging of mitochondria oxidative stress

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Abstract

Two novel Ir(III)–nitroxide conjugates have been synthesized as mitochondria-targeted multi-functional theranostic photosensitizers, capable of simultaneously inducing and dual-modal phosphorescence imaging of mitochondrial oxidative stress under two-photon excitation, thus realizing the photodynamic therapy of cancer and self-assessment of their PDT efficacies.

Graphical abstract: A self-assessed photosensitizer: inducing and dual-modal phosphorescence imaging of mitochondria oxidative stress

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Publication details

The article was received on 09 Oct 2017, accepted on 05 Dec 2017 and first published on 05 Dec 2017


Article type: Communication
DOI: 10.1039/C7CC07797A
Citation: Chem. Commun., 2018, Advance Article
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    A self-assessed photosensitizer: inducing and dual-modal phosphorescence imaging of mitochondria oxidative stress

    Y. Jing, Q. Cao, L. Hao, G. Yang, W. Hu, L. Ji and Z. Mao, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC07797A

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