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Aptamer modified-selenium nanoparticles for dark-field microscopy imaging of nucleolin

Abstract

Selenium nanoparticles (SeNPs) with strong green scattering light serving as light scattering nanoprobes for dark-field microscopy imaging are firstly developed. The SeNPs show good stability, excellent biocompatibility, high light-producing power, and can precisely and specifically target cancer cells with overexpressed nucleolin (NCL) after modification with aptamers, revealing that the SeNPs can act as a good light scattering nanoprobe for bioimaging and biolabeling.

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Publication details

The article was received on 02 Oct 2017, accepted on 13 Nov 2017 and first published on 13 Nov 2017


Article type: Communication
DOI: 10.1039/C7CC07664A
Citation: Chem. Commun., 2017, Accepted Manuscript
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    Aptamer modified-selenium nanoparticles for dark-field microscopy imaging of nucleolin

    M. L. Liu, H. Y. Zou, C. M. Li, R. S. Li and C. Z. Huang, Chem. Commun., 2017, Accepted Manuscript , DOI: 10.1039/C7CC07664A

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