Jump to main content
Jump to site search


Supramolecular block copolymers for gene delivery: enhancement of transfection efficiency by charge regulation

Author affiliations

Abstract

A class of cationic supramolecular block copolymers with readily controlled charges has been exploited. Upon post-synthetic structural optimization, this copolymer exhibits comparable biocompatibility, greatly improved pDNA condensation capability and biostability, and further enhanced transfection efficiency in vitro. This work provides valuable insight into the creation of advanced nonviral vectors for gene delivery.

Graphical abstract: Supramolecular block copolymers for gene delivery: enhancement of transfection efficiency by charge regulation

Back to tab navigation

Supplementary files

Publication details

The article was received on 01 Oct 2017, accepted on 08 Nov 2017 and first published on 08 Nov 2017


Article type: Communication
DOI: 10.1039/C7CC07652E
Citation: Chem. Commun., 2017, Advance Article
  •   Request permissions

    Supramolecular block copolymers for gene delivery: enhancement of transfection efficiency by charge regulation

    W. Yasen, R. Dong, L. Zhou, Y. Huang, D. Guo, D. Chen, C. Li, A. Aini and X. Zhu, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC07652E

Search articles by author

Spotlight

Advertisements