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Base-Catalyzed Thio-Lactamization of 2-(1-Arylvinyl)anilines with CS2 for the Synthesis of Quinoline-2-thiones

Abstract

Here we show that base-catalyzed thio-lactamization of 2-(1-arylvinyl)anilines with CS2 is a powerful methodology to synthesize quinoline-2-thiones. This thio-lactamization use an inexpensive and versatile 2-(1-arylvinyl)anilines, which are easily available from reaction of amines and alkynes. Compared to the known strategy, this method features the advantages like short synthesis step and easily available starting materials.

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Publication details

The article was received on 30 Sep 2017, accepted on 07 Dec 2017 and first published on 07 Dec 2017


Article type: Communication
DOI: 10.1039/C7CC07633A
Citation: Chem. Commun., 2017, Accepted Manuscript
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    Base-Catalyzed Thio-Lactamization of 2-(1-Arylvinyl)anilines with CS2 for the Synthesis of Quinoline-2-thiones

    T. Wang, X. Liu, X. Wang, C. Huo and Z. Quan, Chem. Commun., 2017, Accepted Manuscript , DOI: 10.1039/C7CC07633A

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