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Issue 94, 2017
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Transition metal-free N-fluoroalkylation of amines using cyanurate activated fluoroalcohols

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Abstract

A novel and highly efficient method for N-fluoroalkylation of amines using 2,4,6-tris(fluoroalkoxy)-1,3,5-triazines was developed. This simple approach allowed the N-fluoroalkylation of amines under fast, mild and efficient reaction conditions, without using a transition metal as a catalyst.

Graphical abstract: Transition metal-free N-fluoroalkylation of amines using cyanurate activated fluoroalcohols

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Publication details

The article was received on 23 Sep 2017, accepted on 06 Nov 2017 and first published on 06 Nov 2017


Article type: Communication
DOI: 10.1039/C7CC07428J
Citation: Chem. Commun., 2017,53, 12650-12653
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    Transition metal-free N-fluoroalkylation of amines using cyanurate activated fluoroalcohols

    F. Haghighi, F. Panahi, M. Golbon Haghighi and A. Khalafi-Nezhad, Chem. Commun., 2017, 53, 12650
    DOI: 10.1039/C7CC07428J

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