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Issue 100, 2017
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Sensing the impact of environment on small molecule differentiation of RNA sequences

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Abstract

Using pattern recognition of RNA with small molecules (PRRSM) with fluorescent RNA chemosensors and aminoglycosides, we reveal the impact of changing environmental conditions on the differentiation of a range of RNA structures as well as the ability to predict different sequence/size compositions of five canonical RNA motifs.

Graphical abstract: Sensing the impact of environment on small molecule differentiation of RNA sequences

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Publication details

The article was received on 13 Sep 2017, accepted on 24 Nov 2017 and first published on 28 Nov 2017


Article type: Communication
DOI: 10.1039/C7CC07157D
Citation: Chem. Commun., 2017,53, 13363-13366
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    Sensing the impact of environment on small molecule differentiation of RNA sequences

    C. S. Eubanks and A. E. Hargrove, Chem. Commun., 2017, 53, 13363
    DOI: 10.1039/C7CC07157D

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