Jump to main content
Jump to site search

Issue 88, 2017
Previous Article Next Article

Nickel-catalyzed acetamidation and lactamization of arylboronic acids

Author affiliations

Abstract

A nickel-catalyzed acetamidation and lactamization of arylboronic acids via a one-pot reaction with ynamides and N-hydroxyphthalimide is described. This protocol features with mild reaction conditions and a broad substrate scope, and has been successfully applied to late-stage functionalization of pharmaceuticals. Moreover, control reactions were conducted to elucidate a plausible mechanism.

Graphical abstract: Nickel-catalyzed acetamidation and lactamization of arylboronic acids

Back to tab navigation

Supplementary files

Publication details

The article was received on 08 Sep 2017, accepted on 10 Oct 2017 and first published on 10 Oct 2017


Article type: Communication
DOI: 10.1039/C7CC07055A
Citation: Chem. Commun., 2017,53, 11996-11999
  •   Request permissions

    Nickel-catalyzed acetamidation and lactamization of arylboronic acids

    B. Huang, L. Zeng, Y. Shen and S. Cui, Chem. Commun., 2017, 53, 11996
    DOI: 10.1039/C7CC07055A

Search articles by author

Spotlight

Advertisements