Jump to main content
Jump to site search

Issue 92, 2017
Previous Article Next Article

Catalytic transient leaving group for atom-economic synthesis of allenes from 2-alkynols

Author affiliations

Abstract

An atom economic approach from readily available propargylic alcohols to allenes, the first carboxylation of propargylic alcohols, has been established. Through the cooperative binary catalysis of Pd and a phosphoric acid, the reaction afforded multi-substituted allenoates with a broad scope tolerating useful functional groups. The synthetic potential of the obtained products has been demonstrated.

Graphical abstract: Catalytic transient leaving group for atom-economic synthesis of allenes from 2-alkynols

Back to tab navigation

Supplementary files

Publication details

The article was received on 02 Sep 2017, accepted on 18 Oct 2017 and first published on 18 Oct 2017


Article type: Communication
DOI: 10.1039/C7CC06866B
Citation: Chem. Commun., 2017,53, 12430-12433
  •   Request permissions

    Catalytic transient leaving group for atom-economic synthesis of allenes from 2-alkynols

    W. Zhang, C. Huang, Y. Yuan and S. Ma, Chem. Commun., 2017, 53, 12430
    DOI: 10.1039/C7CC06866B

Search articles by author

Spotlight

Advertisements