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A two-photon excitable and ratiometric fluorogenic nitric oxide photoreleaser and its biological applications

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Abstract

We report for the first time the development of a two-photon excitable NO photoreleaser, CNNO, for ratiometric imaging and tracking of NO release in live cells. CNNO exhibits the merits of spatiotemporal control in both the site-specific NO release in the selected cell culture region and the controllable vasodilation of mouse aorta ex vivo.

Graphical abstract: A two-photon excitable and ratiometric fluorogenic nitric oxide photoreleaser and its biological applications

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Publication details

The article was received on 30 Aug 2017, accepted on 12 Oct 2017 and first published on 12 Oct 2017


Article type: Communication
DOI: 10.1039/C7CC06820D
Citation: Chem. Commun., 2017, Advance Article
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    A two-photon excitable and ratiometric fluorogenic nitric oxide photoreleaser and its biological applications

    X. Xie, J. Fan, M. Liang, Y. Li, X. Jiao, X. Wang and B. Tang, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC06820D

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