Jump to main content
Jump to site search

Issue 86, 2017
Previous Article Next Article

Chiral N,N′-dioxide/Sc(OTf)3 complex-catalyzed asymmetric dearomatization of β-naphthols

Author affiliations

Abstract

An efficient N,N′-dioxide–scandium(III) complex catalytic system has been developed for the asymmetric dearomatization of β-naphthols through conjugate addition to alkynones. A variety of Z-predominated β-naphthalenone compounds were obtained in moderate to high yields with excellent enantioselectivities (up to 98% ee). Moreover, a possible transition state was proposed to explain the origin of the stereoselectivity.

Graphical abstract: Chiral N,N′-dioxide/Sc(OTf)3 complex-catalyzed asymmetric dearomatization of β-naphthols

Back to tab navigation

Supplementary files

Publication details

The article was received on 15 Aug 2017, accepted on 05 Oct 2017 and first published on 05 Oct 2017


Article type: Communication
DOI: 10.1039/C7CC06388A
Citation: Chem. Commun., 2017,53, 11759-11762
  •   Request permissions

    Chiral N,N′-dioxide/Sc(OTf)3 complex-catalyzed asymmetric dearomatization of β-naphthols

    S. Ge, T. Kang, L. Lin, X. Zhang, P. Zhao, X. Liu and X. Feng, Chem. Commun., 2017, 53, 11759
    DOI: 10.1039/C7CC06388A

Search articles by author

Spotlight

Advertisements