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Issue 75, 2017
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Triazolium cyclodextrin click cluster–resin conjugate: an enrichment material for phosphatidylinositol (3,4,5)-triphosphate

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Abstract

UltraLink was functionalized with a triazolium cyclodextrin click cluster (CCC) which provides a well-oriented, multivalent, positively charged binding site for PtdIns(3,4,5)P3. MALDI TOF MS and LC ESI MS/MS MRM analysis of spiked PtdIns(3,4,5)P3 in lipid extract suggest that triazolium CCC–UltraLink conjugate can be used as an enrichment material for PtdIns(3,4,5)P3.

Graphical abstract: Triazolium cyclodextrin click cluster–resin conjugate: an enrichment material for phosphatidylinositol (3,4,5)-triphosphate

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Publication details

The article was received on 07 Aug 2017, accepted on 04 Sep 2017 and first published on 04 Sep 2017


Article type: Communication
DOI: 10.1039/C7CC06151J
Citation: Chem. Commun., 2017,53, 10459-10462
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    Triazolium cyclodextrin click cluster–resin conjugate: an enrichment material for phosphatidylinositol (3,4,5)-triphosphate

    H. T. Le, J. W. Lee, S. C. Park, J. W. Jeong, W. Jung, C. W. Lim, K. P. Kim and T. W. Kim, Chem. Commun., 2017, 53, 10459
    DOI: 10.1039/C7CC06151J

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