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Highly selective tridentate fluorescent probes for visualizing intracellular Mg2+ dynamics without interference from Ca2+ fluctuation

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Abstract

We developed highly selective fluorescent Mg2+ probes based on a novel tridentate Mg2+-selective chelator. The superior selectivity for Mg2+ over Ca2+ enabled the detection of intracellular Mg2+ concentration changes without any response to Ca2+ influx. The new probes are potential keys to elucidating intracellular Mg2+ dynamics under conditions of extremely sharp Ca2+ fluctuation.

Graphical abstract: Highly selective tridentate fluorescent probes for visualizing intracellular Mg2+ dynamics without interference from Ca2+ fluctuation

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Publication details

The article was received on 06 Aug 2017, accepted on 30 Aug 2017 and first published on 30 Aug 2017


Article type: Communication
DOI: 10.1039/C7CC06141B
Citation: Chem. Commun., 2017, Advance Article
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    Highly selective tridentate fluorescent probes for visualizing intracellular Mg2+ dynamics without interference from Ca2+ fluctuation

    Y. Matsui, K. K. Sadhu, S. Mizukami and K. Kikuchi, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC06141B

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