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A single stranded fluorescent peptide probe for targeting collagen in connective tissues

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Abstract

We herein report the construction of a novel single stranded fluorescent collagen mimetic peptide by introducing a bulky FAM dye in the central region rather than the N terminus. Without the need for any prior thermal or ultraviolet treatment, the peptide probe can be conveniently applied to specifically target collagen in connective tissues for fluorescence imaging.

Graphical abstract: A single stranded fluorescent peptide probe for targeting collagen in connective tissues

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Publication details

The article was received on 02 Aug 2017, accepted on 09 Oct 2017 and first published on 09 Oct 2017


Article type: Communication
DOI: 10.1039/C7CC06056D
Citation: Chem. Commun., 2017, Advance Article
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    A single stranded fluorescent peptide probe for targeting collagen in connective tissues

    X. Cai, Z. Liu, S. Zhao, C. Song, S. Dong and J. Xiao, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC06056D

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