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Rational design of a fast and selective near-infrared fluorescent probe for targeted monitoring of endogenous nitric oxide

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Abstract

The real-time monitoring of nitric oxide (NO) at the subcellular level is still a great challenge. To attain this goal, we developed a fast and selective near-infrared (NIR) fluorescent probe for the targeted tracing of endogenous NO. This probe possesses vital features for the real-time detection of intracellular NO including a significant turn-on NIR response, high specificity, and a fast response by a controlled photoinduced electron transfer (PET) process, which is applicable to the real-time monitoring of endogenous NO in mitochondria.

Graphical abstract: Rational design of a fast and selective near-infrared fluorescent probe for targeted monitoring of endogenous nitric oxide

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Publication details

The article was received on 31 Jul 2017, accepted on 30 Aug 2017 and first published on 31 Aug 2017


Article type: Communication
DOI: 10.1039/C7CC05971J
Citation: Chem. Commun., 2017, Advance Article
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    Rational design of a fast and selective near-infrared fluorescent probe for targeted monitoring of endogenous nitric oxide

    J. Tang, Z. Guo, Y. Zhang, B. Bai and W. Zhu, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC05971J

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