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α-Helical peptide vesicles with chiral membranes as enantioselective nanoreactors

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Abstract

We report peptide vesicles with chiral membranes as enantioselective nanoreactors. The peptide vesicles are able to selectively encapsulate only a single enantiomer from a racemic mixture solution through preferential diffusion across the membranes. Notably, the confined space of the vesicle acts as an enantioselective nanoreactor for the encapsulated enantiomer which undergoes further chemical transformations to yield a highly enantiopure product.

Graphical abstract: α-Helical peptide vesicles with chiral membranes as enantioselective nanoreactors

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Publication details

The article was received on 28 Jul 2017, accepted on 13 Sep 2017 and first published on 13 Sep 2017


Article type: Communication
DOI: 10.1039/C7CC05869A
Citation: Chem. Commun., 2017, Advance Article
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    α-Helical peptide vesicles with chiral membranes as enantioselective nanoreactors

    X. Chen, Y. Wang, H. Wang, Y. Kim and M. Lee, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC05869A

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