Issue 72, 2017
From the journal:

Chemical Communications

A modular trigger for the development of selective superoxide probes†

Zuo Hang Yu,‡a   Clive Yik-Sham Chung,‡b   Fung Kit Tang,‡a   Thomas F. Brewerb  and  Ho Yu Au-Yeung ORCID logo *a  

* Corresponding authors

a Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China
E-mail: hoyuay@hku.hk

b Department of Chemistry, University of California, Berkeley, California, USA

Abstract

We report here a new bioinspired copper-based strategy of superoxide sensing and the development of sensitive (>90-fold fluorescence turn-on) and selective superoxide probes for imaging variations in the endogenous superoxide level in various live mammalian cells (HEK293T, HeLa and A431).

Graphical abstract: A modular trigger for the development of selective superoxide probes

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Article information

DOI
https://doi.org/10.1039/C7CC05405J
Article type
Communication
Submitted
13 Jul 2017
Accepted
17 Aug 2017
First published
17 Aug 2017

Chem. Commun., 2017,53, 10042-10045

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A modular trigger for the development of selective superoxide probes

Z. H. Yu, C. Y. Chung, F. K. Tang, T. F. Brewer and H. Y. Au-Yeung, Chem. Commun., 2017, 53, 10042 DOI: 10.1039/C7CC05405J

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