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Syntheses and effectiveness of functional peptide-based RAFT agents

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Abstract

In this study, a series of functional peptide-based RAFT agents were designed and synthesized by the solid-phase supported peptide synthesis method. These novel RAFT agents have enabled chemists to make well-defined peptide–polymer conjugates with complicated topological structures. Additionally, our results have shown an unexpected reaction that takes place during these syntheses, and the conversion of a nitrile group to a carboxamide group has been evidently elucidated and unambiguously confirmed.

Graphical abstract: Syntheses and effectiveness of functional peptide-based RAFT agents

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Publication details

The article was received on 10 Jul 2017, accepted on 30 Aug 2017 and first published on 30 Aug 2017


Article type: Communication
DOI: 10.1039/C7CC05316A
Citation: Chem. Commun., 2017, Advance Article
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    Syntheses and effectiveness of functional peptide-based RAFT agents

    C. Chen, F. Kong, X. Wei and S. H. Thang, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC05316A

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