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A light-up endoplasmic reticulum probe based on a rational design of red-emissive fluorogens with aggregation-induced emission

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Abstract

Fine-tuning electron acceptors through changing one cyano group to an amide generates a more stable and emissive fluorophore with the character of aggregation-induced emission. Conjugation between the new fluorophore and CFFKDEL generated an excellent ER targeting light-up probe with high specificity and good photostability.

Graphical abstract: A light-up endoplasmic reticulum probe based on a rational design of red-emissive fluorogens with aggregation-induced emission

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Publication details

The article was received on 06 Jul 2017, accepted on 19 Aug 2017 and first published on 21 Aug 2017


Article type: Communication
DOI: 10.1039/C7CC05205G
Citation: Chem. Commun., 2017, Advance Article
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    A light-up endoplasmic reticulum probe based on a rational design of red-emissive fluorogens with aggregation-induced emission

    C. Zhang, X. Cai, S. Xu, R. Zhan, W. Jien and B. Liu, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC05205G

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