Jump to main content
Jump to site search

Issue 70, 2017
Previous Article Next Article

Condensing the information in DNA with double-headed nucleotides

Author affiliations

Abstract

A normal duplex holds as many Watson–Crick base pairs as the number of nucleotides in its constituent strands. Here we establish that single nucleotides can be designed to functionally imitate dinucleotides without compromising binding affinity. This effectively allows sequence information to be more compact and concentrated to fewer phosphates.

Graphical abstract: Condensing the information in DNA with double-headed nucleotides

Back to tab navigation

Supplementary files

Publication details

The article was received on 29 Jun 2017, accepted on 07 Aug 2017 and first published on 07 Aug 2017


Article type: Communication
DOI: 10.1039/C7CC05047J
Citation: Chem. Commun., 2017,53, 9717-9720
  •   Request permissions

    Condensing the information in DNA with double-headed nucleotides

    M. Hornum, P. K. Sharma, C. Reslow-Jacobsen, P. Kumar, M. Petersen and P. Nielsen, Chem. Commun., 2017, 53, 9717
    DOI: 10.1039/C7CC05047J

Search articles by author

Spotlight

Advertisements