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Phosphorus dendrimers for nanomedicine

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Abstract

From biomaterials to imaging, and from drug delivery to drugs by themselves, phosphorus-containing dendrimers offer a large palette of biological properties, depending essentially on their types of terminal functions. The most salient examples of phosphorus dendrimers used for the elaboration of bio-chips and of supports for cell cultures, for imaging biological events, and for carrying and delivering drugs or biomacromolecules are presented in this feature article. Several phosphorus dendrimers can be considered also as drugs per se (by themselves) in particular to fight against cancers, neurodegenerative diseases, and inflammation, both in vitro and in vivo. Toxicity assays are also reported.

Graphical abstract: Phosphorus dendrimers for nanomedicine

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Publication details

The article was received on 26 Jun 2017, accepted on 18 Jul 2017 and first published on 18 Jul 2017


Article type: Feature Article
DOI: 10.1039/C7CC04949H
Citation: Chem. Commun., 2017, Advance Article
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    Phosphorus dendrimers for nanomedicine

    A. Caminade, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC04949H

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