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Issue 68, 2017
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Fluorescence-switching RNA for detection of bacterial ribosomes

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Abstract

We have developed an efficient chemical system that allows quantification of bacterial ribosomes by fluorescence-based analysis. The key component in the system is the exciton-controlled fluorescent RNA aptamer, which recognizes neomycin B. The intensity of fluorescence from such a ribosome-sensing system increased drastically in the presence of Escherichia coli.

Graphical abstract: Fluorescence-switching RNA for detection of bacterial ribosomes

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Publication details

The article was received on 21 Jun 2017, accepted on 17 Jul 2017 and first published on 18 Jul 2017


Article type: Communication
DOI: 10.1039/C7CC04818A
Citation: Chem. Commun., 2017,53, 9406-9409
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    Fluorescence-switching RNA for detection of bacterial ribosomes

    L. Guo and A. Okamoto, Chem. Commun., 2017, 53, 9406
    DOI: 10.1039/C7CC04818A

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