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Cooperative, ion-sensitive co-assembly of tripeptide hydrogels

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Abstract

Peptide co-assembly is of interest for the development of functional supramolecular biomaterials. Herein, computational simulations were combined with experimental validation to aid the design and understanding of cooperative co-assembly of a structure-forming tripeptide (FFD) and a functional copper-binding tripeptide (GHK) leading to hydrogel formation in response to complexation with copper ions.

Graphical abstract: Cooperative, ion-sensitive co-assembly of tripeptide hydrogels

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Publication details

The article was received on 20 Jun 2017, accepted on 07 Aug 2017 and first published on 07 Aug 2017


Article type: Communication
DOI: 10.1039/C7CC04796G
Citation: Chem. Commun., 2017, Advance Article
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    Cooperative, ion-sensitive co-assembly of tripeptide hydrogels

    Y. M. Abul-Haija, G. G. Scott, J. K. Sahoo, T. Tuttle and R. V. Ulijn, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC04796G

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