An enzyme-free DNA walker that moves on the surface of functionalized magnetic microparticles and its biosensing analysis

Ningxing Li; Jiao Zheng; Chunrong Li; Xinxin Wang; Xinghu Ji; Zhike He

doi:10.1039/C7CC04547F

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An enzyme-free DNA walker that moves on the surface of functionalized magnetic microparticles and its biosensing analysis†

Ningxing Li,^a Jiao Zheng,^a Chunrong Li,^a Xinxin Wang,^a Xinghu Ji^a and Zhike He

*^a

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* Corresponding authors

^a Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, P. R. China
E-mail: zhkhe@whu.edu.cn

Abstract

An enzyme-free stochastic DNA walker propelled by a single catalytic or double catalytic DNA assembly has been constructed. The application of the proposed DNA walking biosensor was successfully expanded to the detection of DNA and the enzymatic activity of T4 polynucleotide kinase.

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Article information

DOI: https://doi.org/10.1039/C7CC04547F
Article type: Communication
Submitted: 12 Jun 2017
Accepted: 05 Jul 2017
First published: 05 Jul 2017

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Chem. Commun., 2017,53, 8486-8488

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An enzyme-free DNA walker that moves on the surface of functionalized magnetic microparticles and its biosensing analysis

N. Li, J. Zheng, C. Li, X. Wang, X. Ji and Z. He, Chem. Commun., 2017, 53, 8486 DOI: 10.1039/C7CC04547F

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Chemical Communications

An enzyme-free DNA walker that moves on the surface of functionalized magnetic microparticles and its biosensing analysis†

Abstract

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An enzyme-free DNA walker that moves on the surface of functionalized magnetic microparticles and its biosensing analysis

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