Jump to main content
Jump to site search

Issue 54, 2017
Previous Article Next Article

Pd(0)-Catalyzed intramolecular arylative dearomatization of β-naphthols

Author affiliations

Abstract

An efficient Pd(0)-catalyzed intramolecular arylative dearomatization of β-naphthols is described. Using Q-Phos as a ligand, the arylative dearomatization reaction proceeded smoothly affording excellent yields and chemoselectivity even when the catalyst loading was reduced to 0.1 mol%. This method offers an efficient access to a series of structurally diverse spirocarbocycles. Preliminary investigation indicates that an enantioselective reaction is feasible in the presence of a chiral phosphoramidite ligand.

Graphical abstract: Pd(0)-Catalyzed intramolecular arylative dearomatization of β-naphthols

Back to tab navigation

Supplementary files

Publication details

The article was received on 25 May 2017, accepted on 13 Jun 2017 and first published on 13 Jun 2017


Article type: Communication
DOI: 10.1039/C7CC04022A
Citation: Chem. Commun., 2017,53, 7553-7556
  •   Request permissions

    Pd(0)-Catalyzed intramolecular arylative dearomatization of β-naphthols

    R. Xu, P. Yang and S. You, Chem. Commun., 2017, 53, 7553
    DOI: 10.1039/C7CC04022A

Search articles by author

Spotlight

Advertisements