Jump to main content
Jump to site search

Issue 51, 2017
Previous Article Next Article

Cobaloxime-catalyzed hydration of terminal alkynes without acidic promoters

Author affiliations

Abstract

Cobaloxime (Co(dmgBF2)2·2H2O), an inexpensive first-row transition-metal complex, catalyzed hydration of terminal alkynes gave the corresponding methyl ketones in good to excellent yields under neutral conditions (additional protic acids and silver salts are not required). A wide range of functional groups, such as allyl ether, benzyl ethers, carboxylic esters, imides, amides, nitro, and halogens, were tolerated. The mild reaction conditions together with the inexpensive feature and easy availability of the catalyst well address the current challenges in the field of alkyne hydration.

Graphical abstract: Cobaloxime-catalyzed hydration of terminal alkynes without acidic promoters

Back to tab navigation

Supplementary files

Publication details

The article was received on 20 May 2017, accepted on 06 Jun 2017 and first published on 06 Jun 2017


Article type: Communication
DOI: 10.1039/C7CC03919K
Citation: Chem. Commun., 2017,53, 6926-6929
  •   Request permissions

    Cobaloxime-catalyzed hydration of terminal alkynes without acidic promoters

    S. Hou, H. Yang, B. Cheng, H. Zhai and Y. Li, Chem. Commun., 2017, 53, 6926
    DOI: 10.1039/C7CC03919K

Search articles by author

Spotlight

Advertisements