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Issue 51, 2017
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A single quantum dot-based nanosensor for the signal-on detection of DNA methyltransferase

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Abstract

We develop a single quantum dot (QD)-based nanosensor for the signal-on detection of DNA methyltransferase (MTase). By integration of single-molecule counting with the QD-based fluorescence resonance energy transfer (FRET), the proposed nanosensor can sensitively detect DNA MTase with a detection limit of as low as 0.002 U mL−1, and it can be further applied for inhibitor screening and accurate detection of DNA MTase in complex biological samples.

Graphical abstract: A single quantum dot-based nanosensor for the signal-on detection of DNA methyltransferase

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Publication details

The article was received on 13 May 2017, accepted on 05 Jun 2017 and first published on 06 Jun 2017


Article type: Communication
DOI: 10.1039/C7CC03736H
Citation: Chem. Commun., 2017,53, 6868-6871
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    A single quantum dot-based nanosensor for the signal-on detection of DNA methyltransferase

    F. Ma, W. Liu, B. Tang and C. Zhang, Chem. Commun., 2017, 53, 6868
    DOI: 10.1039/C7CC03736H

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