Jump to main content
Jump to site search


A fluorescence turn-on probe for human (bovine) serum albumin based on the hydrolysis of dioxaborine group promoted by the proteins

Abstract

A fluorescence “off-on” probe CBF, constructed by incorporating a dioxaborine unit into a microenvironment-sensitive fluorophore, was developed for serum album (SA). Upon binding to SA, the dioxaborine group in CBF was hydrolyzed into β-diketonate, which triggered dramatic fluorescence enhancement (over 1000-fold) along with remarkable blue-shift (about 100 nm). The bioimaging results suggested that more SA were taken in by cancer cells.

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was accepted on 16 May 2017 and first published on 19 May 2017


Article type: Communication
DOI: 10.1039/C7CC03587J
Citation: Chem. Commun., 2017, Accepted Manuscript
  •   Request permissions

    A fluorescence turn-on probe for human (bovine) serum albumin based on the hydrolysis of dioxaborine group promoted by the proteins

    Q. Sun, W. Wang, Z. Chen, Y. Yao, W. Zhang, L. Duan and J. Qian, Chem. Commun., 2017, Accepted Manuscript , DOI: 10.1039/C7CC03587J

Search articles by author