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Cell-sized mechanosensitive and biosensing compartment programmed with DNA

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Abstract

The bottom-up construction of cell-sized compartments programmed with DNA that are capable of sensing the chemical and physical environment remains challenging in synthetic cell engineering. Here, we construct mechanosensitive liposomes with biosensing capability by expressing the E. coli channel MscL and a calcium biosensor using cell-free expression.

Graphical abstract: Cell-sized mechanosensitive and biosensing compartment programmed with DNA

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Publication details

The article was received on 04 May 2017, accepted on 12 May 2017 and first published on 12 May 2017


Article type: Communication
DOI: 10.1039/C7CC03455E
Citation: Chem. Commun., 2017, Advance Article
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    Cell-sized mechanosensitive and biosensing compartment programmed with DNA

    S. Majumder, J. Garamella, Y. Wang, M. DeNies, V. Noireaux and A. P. Liu, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC03455E

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