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Issue 79, 2017
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Lipid radicals cause light-induced retinal degeneration

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Abstract

Age-related macular degeneration (AMD) is the leading cause of blindness worldwide. Although the cause of AMD remains unknown, lipid peroxidation (LPO) end-products are critical molecules for its development. Herein, we report the imaging of lipid radicals, which are key factors in the LPO reaction, and therapeutic information using animal models.

Graphical abstract: Lipid radicals cause light-induced retinal degeneration

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Publication details

The article was received on 02 May 2017, accepted on 12 Sep 2017 and first published on 12 Sep 2017


Article type: Communication
DOI: 10.1039/C7CC03387G
Citation: Chem. Commun., 2017,53, 10922-10925
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    Lipid radicals cause light-induced retinal degeneration

    M. Enoki, S. Shinto, Y. Matsuoka, A. Otsuka, S. Kaidzu, M. Tanito, T. Shibata, K. Uchida, A. Ohira, M. Yamato and K. Yamada, Chem. Commun., 2017, 53, 10922
    DOI: 10.1039/C7CC03387G

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