Jump to main content
Jump to site search


Copper-mediated C–H cyanation of (hetero)arenes with ethyl (ethoxymethylene)cyanoacetate as a cyanating agent

Author affiliations

Abstract

A copper-mediated direct C–H cyanation of (hetero)arenes with ethyl (ethoxymethylene)cyanoacetate as a safe cyanating agent has been successfully developed by using molecular oxygen as the oxidant. The reaction tolerates a variety of functional groups and provides a facile and efficient method for the synthesis of a wide range of (hetero)aryl nitriles.

Graphical abstract: Copper-mediated C–H cyanation of (hetero)arenes with ethyl (ethoxymethylene)cyanoacetate as a cyanating agent

Back to tab navigation

Supplementary files

Publication details

The article was received on 02 May 2017, accepted on 06 Jun 2017 and first published on 06 Jun 2017


Article type: Communication
DOI: 10.1039/C7CC03384B
Citation: Chem. Commun., 2017, Advance Article
  •   Request permissions

    Copper-mediated C–H cyanation of (hetero)arenes with ethyl (ethoxymethylene)cyanoacetate as a cyanating agent

    C. Qi, X. Hu and H. Jiang, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC03384B

Search articles by author

Spotlight

Advertisements