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Issue 52, 2017
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Elucidation of the elusive structure and formula of the active pharmaceutical ingredient bismuth subgallate by continuous rotation electron diffraction

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Abstract

Bismuth subgallate has been used in wound and gastrointestinal therapy for over a century. The combination of continuous rotation electron diffraction and sample cooling finally revealed its structure as a coordination polymer. The structure provides insight regarding its formula, poor solubility, acid resistance and previously unreported gas sorption properties.

Graphical abstract: Elucidation of the elusive structure and formula of the active pharmaceutical ingredient bismuth subgallate by continuous rotation electron diffraction

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Publication details

The article was received on 25 Apr 2017, accepted on 07 Jun 2017 and first published on 07 Jun 2017


Article type: Communication
DOI: 10.1039/C7CC03180G
Citation: Chem. Commun., 2017,53, 7018-7021
  • Open access: Creative Commons BY license
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    Elucidation of the elusive structure and formula of the active pharmaceutical ingredient bismuth subgallate by continuous rotation electron diffraction

    Y. Wang, S. Takki, O. Cheung, H. Xu, W. Wan, L. Öhrström and A. K. Inge, Chem. Commun., 2017, 53, 7018
    DOI: 10.1039/C7CC03180G

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