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Issue 55, 2017
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pH-Responsive near-infrared fluorescent cyanine dyes for molecular imaging based on pH sensing

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Abstract

Indocyanine green (ICG) derivatives having nucleophilic substituents were synthesized as pH-responsive near-infrared dyes. pH-responsive dyes 1-C with closed-ring structures smoothly internalized and converted to emissive open-ring structures 1-O in response to relatively low pHs in acidic intracellular compartments of HeLa cells.

Graphical abstract: pH-Responsive near-infrared fluorescent cyanine dyes for molecular imaging based on pH sensing

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Publication details

The article was received on 20 Apr 2017, accepted on 19 Jun 2017 and first published on 19 Jun 2017


Article type: Communication
DOI: 10.1039/C7CC03035E
Citation: Chem. Commun., 2017,53, 7792-7795
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    pH-Responsive near-infrared fluorescent cyanine dyes for molecular imaging based on pH sensing

    K. Miki, K. Kojima, K. Oride, H. Harada, A. Morinibu and K. Ohe, Chem. Commun., 2017, 53, 7792
    DOI: 10.1039/C7CC03035E

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