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pH-Responsive Near-Infrared Fluorescent Cyanine Dyes for Molecular Imaging Based on pH Sensing

Abstract

Indocyanine green (ICG) derivatives having nucleophilic substituents were synthesized as a pH-responsive near-infrared dye. pH-Responsive dyes 1-C with closed-ring structures smoothly internalized and converted to emissive open-ring structures 1-O in response to relatively low pH in acidic intracellular compartments of HeLa cells.

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Publication details

The article was received on 20 Apr 2017, accepted on 19 Jun 2017 and first published on 19 Jun 2017


Article type: Communication
DOI: 10.1039/C7CC03035E
Citation: Chem. Commun., 2017, Accepted Manuscript
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    pH-Responsive Near-Infrared Fluorescent Cyanine Dyes for Molecular Imaging Based on pH Sensing

    K. Miki, K. Kojima, K. Oride, H. Harada, A. Morinibu and K. Ohe, Chem. Commun., 2017, Accepted Manuscript , DOI: 10.1039/C7CC03035E

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