Jump to main content
Jump to site search

Issue 42, 2017
Previous Article Next Article

Copper-catalyzed remote (δ) C(sp3)–H bond amination: a practical strategy to construct pyrrolidine derivatives

Author affiliations

Abstract

We report a copper-catalyzed remote C(sp3)–H bond amination reaction that converts acyclic amines to pyrrolidines. This reaction occurs selectively at the carbon δ to the amine functionality. Primary, secondary and tertiary C–H bonds are all suitable for the amination reactions in the presence of an inexpensive and commercially available copper catalyst.

Graphical abstract: Copper-catalyzed remote (δ) C(sp3)–H bond amination: a practical strategy to construct pyrrolidine derivatives

Back to tab navigation

Supplementary files

Publication details

The article was received on 05 Apr 2017, accepted on 04 May 2017 and first published on 04 May 2017


Article type: Communication
DOI: 10.1039/C7CC02624B
Citation: Chem. Commun., 2017,53, 5744-5747
  •   Request permissions

    Copper-catalyzed remote (δ) C(sp3)–H bond amination: a practical strategy to construct pyrrolidine derivatives

    D. Meng, Y. Tang, J. Wei, X. Shi and M. Yang, Chem. Commun., 2017, 53, 5744
    DOI: 10.1039/C7CC02624B

Search articles by author

Spotlight

Advertisements