Jump to main content
Jump to site search


Temperature switchable Brønsted acid-promoted selective syntheses of spiro-indolenines and quinolines

Author affiliations

Abstract

A high-yielding, temperature switchable divergent approach towards the synthesis of either spiro-indolenines or quinolines is described, starting from easily available indolyl ynones. The application of TFA at rt promotes the dearomatization of the indole, resulting in the formation of the spiro-indolenine, while at higher temperature, rearrangement results in the formation of the quinoline.

Graphical abstract: Temperature switchable Brønsted acid-promoted selective syntheses of spiro-indolenines and quinolines

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 04 Apr 2017, accepted on 26 Apr 2017 and first published on 26 Apr 2017


Article type: Communication
DOI: 10.1039/C7CC02580G
Citation: Chem. Commun., 2017, Advance Article
  •   Request permissions

    Temperature switchable Brønsted acid-promoted selective syntheses of spiro-indolenines and quinolines

    P. Fedoseev and E. Van der Eycken, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC02580G

Search articles by author