Jump to main content
Jump to site search

Issue 44, 2017
Previous Article Next Article

A general diastereoselective synthesis of highly functionalized ferrocenyl ambiphiles enabled on a large scale by electrochemical purification

Author affiliations

Abstract

A general synthesis of highly functionalized ferrocenes, which include (P,B)- and (N,B)-ambiphiles, has been developed at a multigram scale. Diastereoselective stepwise modification of di-tert-butylated ferrocenes included the unprecedented separation of electroactive species. Bulky alkyl groups on ferrocenes ensure planar chirality of ambiphiles and enforce closer proximity of antagonist Lewis functions.

Graphical abstract: A general diastereoselective synthesis of highly functionalized ferrocenyl ambiphiles enabled on a large scale by electrochemical purification

Back to tab navigation

Supplementary files

Publication details

The article was received on 30 Mar 2017, accepted on 10 May 2017 and first published on 11 May 2017


Article type: Communication
DOI: 10.1039/C7CC02469J
Citation: Chem. Commun., 2017,53, 6017-6020
  •   Request permissions

    A general diastereoselective synthesis of highly functionalized ferrocenyl ambiphiles enabled on a large scale by electrochemical purification

    E. Lerayer, P. Renaut, J. Roger, N. Pirio, H. Cattey, C. H. Devillers, D. Lucas and J. Hierso, Chem. Commun., 2017, 53, 6017
    DOI: 10.1039/C7CC02469J

Search articles by author

Spotlight

Advertisements