Jump to main content
Jump to site search


A deciduous directing group approach for the addition of aryl and vinyl nucleophiles to maleimides

Author affiliations

Abstract

A Rh(III)-catalyzed C–H activation followed by conjugate addition to maleimides, using carboxylic acid as a traceless/deciduous directing group, to formally furnish a Csp2–Csp3 bond is presented. For the first time, derivatives of acrylic acid have been shown as surrogates for the unstable and expensive alkenyl boronic acids.

Graphical abstract: A deciduous directing group approach for the addition of aryl and vinyl nucleophiles to maleimides

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 28 Mar 2017, accepted on 15 May 2017 and first published on 15 May 2017


Article type: Communication
DOI: 10.1039/C7CC02392H
Citation: Chem. Commun., 2017, Advance Article
  •   Request permissions

    A deciduous directing group approach for the addition of aryl and vinyl nucleophiles to maleimides

    K. R. Bettadapur, V. Lanke and K. R. Prabhu, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC02392H

Search articles by author