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Photo-cleavable analog of BAPTA for the fast and efficient release of Ca2+

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Abstract

A new photocleavable analog of BAPTA chelating ligand has a high affinity towards Ca2+ ions (K = 2.5 × 106 M−1). The use of photolabile 3-(hydroxymethyl)-2-naphthol core in the design of photo-BAPTA allows for the efficient (Φ = 0. 63) and very fast (τ < 12 μs) release of Ca2+ ions upon 300 or 350 nm irradiation.

Graphical abstract: Photo-cleavable analog of BAPTA for the fast and efficient release of Ca2+

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Publication details

The article was received on 17 Mar 2017, accepted on 03 Apr 2017 and first published on 05 Apr 2017


Article type: Communication
DOI: 10.1039/C7CC02056B
Citation: Chem. Commun., 2017, Advance Article
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    Photo-cleavable analog of BAPTA for the fast and efficient release of Ca2+

    M. V. Sutton, M. McKinley, R. Kulasekharan and V. V. Popik, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC02056B

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