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Palladium-Catalyzed Benzofuran and Indole Synthesis by Multiple C–H Functionalizations

Abstract

Heterocycle compounds are commonly found in the core structure of many pharmaceuticals, natural products, and agrochemicals thus spurring intensive research for conducting their synthesis in a mild and simpler way. Over the years, a host of different strategies has been introduced in an effort for their formation. In this context, significant attention has been gained by methodologies that ensure both step as well as atom efficiency. Synthesis of heterocyclic moieties via multiple C–H activation was found to fulfill these expectations besides guaranteeing the use of starting materials which are easily procurable. This review is focussed on the current development in the field of benzofuran and indole synthesis using multiple C–H functionalization strategy.

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Publication details

The article was received on 17 Mar 2017, accepted on 15 May 2017 and first published on 15 May 2017


Article type: Feature Article
DOI: 10.1039/C7CC02053H
Citation: Chem. Commun., 2017, Accepted Manuscript
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    Palladium-Catalyzed Benzofuran and Indole Synthesis by Multiple C–H Functionalizations

    D. Maiti, S. Agasti and A. Dey, Chem. Commun., 2017, Accepted Manuscript , DOI: 10.1039/C7CC02053H

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