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Stimulated Raman scattering of polymer nanoparticles for multiplexed live-cell imaging

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Abstract

A novel nanoparticle-based imaging strategy is introduced that couples biocompatible organic nanoparticles and stimulated Raman scattering (SRS) microscopy. Polymer nanoparticles with vibrational labels incorporated were readily prepared for multi-color SRS imaging with excellent photo-stability. The Raman-active polymer dots are nontoxic, rapidly enter various cell types, and are applied in multiplexed cell-type sorting.

Graphical abstract: Stimulated Raman scattering of polymer nanoparticles for multiplexed live-cell imaging

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Publication details

The article was received on 10 Mar 2017, accepted on 25 Apr 2017 and first published on 25 Apr 2017


Article type: Communication
DOI: 10.1039/C7CC01860F
Citation: Chem. Commun., 2017, Advance Article
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    Stimulated Raman scattering of polymer nanoparticles for multiplexed live-cell imaging

    F. Hu, S. D. Brucks, T. H. Lambert, L. M. Campos and W. Min, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC01860F

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