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A tumor-specific and mitochondria-targeted fluorescent probe for real-time sensing of hypochlorite in living cells

Abstract

A biotin-rhodamine-TPP conjugate (BiTClO) was reported as a real-time (within 10 s) fluorescent probe for sensing of mitochondrial hypochlorite with excellent selectivity and high sensitivity (0.21 M). Moreover, it is the first tumor-specific and mitochondria-targeted fluorescent probe applied in cell imaging.

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Publication details

The article was received on 04 Mar 2017, accepted on 18 Apr 2017 and first published on 18 Apr 2017


Article type: Communication
DOI: 10.1039/C7CC01679D
Citation: Chem. Commun., 2017, Accepted Manuscript
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    A tumor-specific and mitochondria-targeted fluorescent probe for real-time sensing of hypochlorite in living cells

    X. Yu, K. Li, J. Hou and J. Yang, Chem. Commun., 2017, Accepted Manuscript , DOI: 10.1039/C7CC01679D

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