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Issue 40, 2017
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A tumor-specific and mitochondria-targeted fluorescent probe for real-time sensing of hypochlorite in living cells

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Abstract

A biotin–rhodamine–TPP conjugate (BiTClO) was reported as a real-time (within 10 s) fluorescent probe for the sensing of mitochondrial hypochlorite with excellent selectivity and high sensitivity (0.21 μM). Moreover, it is the first tumor-specific and mitochondria-targeted fluorescent probe applied in cell imaging.

Graphical abstract: A tumor-specific and mitochondria-targeted fluorescent probe for real-time sensing of hypochlorite in living cells

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Publication details

The article was received on 04 Mar 2017, accepted on 18 Apr 2017 and first published on 18 Apr 2017


Article type: Communication
DOI: 10.1039/C7CC01679D
Citation: Chem. Commun., 2017,53, 5539-5541
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    A tumor-specific and mitochondria-targeted fluorescent probe for real-time sensing of hypochlorite in living cells

    K. Li, J. Hou, J. Yang and X. Yu, Chem. Commun., 2017, 53, 5539
    DOI: 10.1039/C7CC01679D

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