Jump to main content
Jump to site search

Issue 29, 2017
Previous Article Next Article

A chiral cobalt(II) complex catalyzed asymmetric formal [3+2] cycloaddition for the synthesis of 1,2,4-triazolines

Author affiliations

Abstract

A highly efficient catalytic asymmetric formal [3+2] cycloaddition reaction of 5-alkoxyoxazoles with azodicarboxylate compounds has been realized by a chiral N,N′-dioxide/Co(BF4)2·6H2O complex. A series of poly-substituted 1,2,4-triazolines compounds were obtained in moderate to excellent yields (70–99%) with excellent enantioselectivities (82–98% ee).

Graphical abstract: A chiral cobalt(ii) complex catalyzed asymmetric formal [3+2] cycloaddition for the synthesis of 1,2,4-triazolines

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Feb 2017, accepted on 14 Mar 2017 and first published on 15 Mar 2017


Article type: Communication
DOI: 10.1039/C7CC01278K
Citation: Chem. Commun., 2017,53, 4077-4079
  •   Request permissions

    A chiral cobalt(II) complex catalyzed asymmetric formal [3+2] cycloaddition for the synthesis of 1,2,4-triazolines

    B. Ma, W. Luo, L. Lin, X. Liu and X. Feng, Chem. Commun., 2017, 53, 4077
    DOI: 10.1039/C7CC01278K

Search articles by author

Spotlight

Advertisements