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Issue 26, 2017
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Facile synthesis of chlorin bioconjugates by a series of click reactions

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Abstract

A multifunctional chlorin platform appended with four short polyethylene glycols and a carboxylate-linker allows rapid conjugation to biotargeting motifs such as proteins and oligonucleotides. The stability and photophysical properties of the chlorin enable development of diagnostics, imaging, molecular tracking, and theranostics.

Graphical abstract: Facile synthesis of chlorin bioconjugates by a series of click reactions

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Publication details

The article was received on 16 Feb 2017, accepted on 28 Feb 2017 and first published on 02 Mar 2017


Article type: Communication
DOI: 10.1039/C7CC01265A
Citation: Chem. Commun., 2017,53, 3773-3776
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    Facile synthesis of chlorin bioconjugates by a series of click reactions

    J. Gonzales, N. V. S. D. K. Bhupathiraju, W. Perea, H. Chu, N. Berisha, V. Bueno, N. Dodic, J. Rozenberg, N. L. Greenbaum and C. M. Drain, Chem. Commun., 2017, 53, 3773
    DOI: 10.1039/C7CC01265A

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