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Issue 51, 2017
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Incorporation studies of clickable ceramides in Jurkat cell plasma membranes

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Abstract

The incorporation properties of ceramide analogues for click chemistry in Jurkat T cells were investigated. The analogues varied in the acyl chain length and the position of the functional group for click chemistry. Fluorescence microscopy studies including anisotropy and quenching experiments showed significant differences in the accessibility of the functional group indicating different incorporation properties into the plasma membrane.

Graphical abstract: Incorporation studies of clickable ceramides in Jurkat cell plasma membranes

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Publication details

The article was received on 15 Feb 2017, accepted on 26 May 2017 and first published on 31 May 2017


Article type: Communication
DOI: 10.1039/C7CC01220A
Citation: Chem. Commun., 2017,53, 6836-6839
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    Incorporation studies of clickable ceramides in Jurkat cell plasma membranes

    T. Walter, J. Schlegel, A. Burgert, A. Kurz, J. Seibel and M. Sauer, Chem. Commun., 2017, 53, 6836
    DOI: 10.1039/C7CC01220A

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