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α,β-Functionalization of Saturated Ketones with Anthranils via Cu-Catalyzed Sequential Dehydrogenation/Aza-Michael Addition/Annulation Cascade Reactions in One-Pot

Abstract

An efficient method to access functionalized quinolines from the readily available saturated ketones and anthranils have been explored. This one-pot cascade reaction involves the in situ generation of α,β-unsaturated ketones by the copper catalysed dehydrogenation of saturated ketones followed by the aza-Michael addition of anthranils and subsequent annulation.

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Publication details

The article was received on 14 Feb 2017, accepted on 13 Apr 2017 and first published on 19 Apr 2017


Article type: Communication
DOI: 10.1039/C7CC01195D
Citation: Chem. Commun., 2017, Accepted Manuscript
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    α,β-Functionalization of Saturated Ketones with Anthranils via Cu-Catalyzed Sequential Dehydrogenation/Aza-Michael Addition/Annulation Cascade Reactions in One-Pot

    D. K. Tiwari, D. K. Tiwari, P. Mandalaparthi , S. B. Wakade and J. B. Nanubolu, Chem. Commun., 2017, Accepted Manuscript , DOI: 10.1039/C7CC01195D

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